Trial Review

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Trial registered on ANZCTR


Registration number
ACTRN12605000097640
Ethics application status
Approved
Date submitted
5/08/2005
Date registered
8/08/2005
Date last updated
19/01/2006
Type of registration
Retrospectively registered

Titles & IDs
Public title
Power training in older adults
Scientific title
Optimal load for increasing muscle power during explosive resistance training in older adults
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Muscle power 178 0
Condition category
Condition code
Musculoskeletal 201 201 0 0
Normal musculoskeletal and cartilage development and function

Intervention/exposure
Study type
Interventional
Description of intervention(s) / exposure
Participants were randomised to explosive resistance training at 20%, 50%, or 80% of maximum dynamic muscle strength (1RM) or a non-training control group for 8-12 weeks. Participants randomised to training groups, exercised twice a week performing 3 sets of 8 rapid concentric/slow eccentric repetitions for 5 exercises (leg press, chest press, leg extension, seated row, leg flexion) using Keiser pneumatic resistance training machines. Control group participants maintained their usual physical activity levels.
Intervention code [1] 125 0
Other interventions
Comparator / control treatment
Non-training control group for 8-12 weeks.
Control group
Dose comparison

Outcomes
Primary outcome [1] 241 0
Peak Muscle Power
Timepoint [1] 241 0
At baseline and 8 or 12 weeks.
Secondary outcome [1] 544 0
Maximal dynamic muscle strength
Timepoint [1] 544 0
At baseline and 8 or 12 weeks.
Secondary outcome [2] 545 0
Local muscular endurance
Timepoint [2] 545 0
At baseline and 8 or 12 weeks.
Secondary outcome [3] 546 0
Balance (posturography)
Timepoint [3] 546 0
At baseline and 8 or 12 weeks.
Secondary outcome [4] 547 0
Fat free mass
Timepoint [4] 547 0
At baseline and 8 or 12 weeks.
Secondary outcome [5] 548 0
Blood pressure during maximal dynamic strength testing
Timepoint [5] 548 0
At baseline

Eligibility
Key inclusion criteria
Aged 60 years or older, living independently, willing to be randomised to experimental or control groups, and be able to attend scheduled testing and training sessions.
Minimum age
60 Years
Maximum age
Not stated
Sex
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
Regular participation in strength/power training/sports (>/= 1 day per week) during the past 6 months, acute or terminal illness, acute myocardial infarction in the past 6 months, unstable cardiovascular disease, uncontrolled diabetes or other metabolic disease, disorders of the nervous system disrupting voluntary movement, severe functional limitation or balance disorders (unable to walk unaided), upper or lower extremity fracture within the past 3 months, arm or leg amputation, currently symptomatic hernia/haemorrhoids, musculoskeletal disease/injury severely restricting voluntary movement, cognitive impairment.

Study design
Purpose of the study
Educational / counselling / training
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Group allocation was concelled in opaque envelopes by an individual not involved with study participants
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Permuted block randomization stratified by gender was generated using a computerized randomization program
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?



Intervention assignment
Factorial
Other design features
Phase
Type of endpoint/s
Efficacy
Statistical methods / analysis

Recruitment
Recruitment status
Completed
Date of first participant enrolment
Anticipated
28/03/2002
Actual
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
Actual
Sample size
Target
112
Accrual to date
Final
Recruitment in Australia
Recruitment state(s)

Funding & Sponsors
Funding source category [1] 256 0
University
Name [1] 256 0
The University of Sydney
Country [1] 256 0
Australia
Primary sponsor type
University
Name
The University of Sydney
Address
Country
Australia
Secondary sponsor category [1] 195 0
None
Name [1] 195 0
None
Address [1] 195 0
Country [1] 195 0

Ethics approval
Ethics application status
Approved
Ethics committee name [1] 1083 0
The University of Sydney - Human Research Ethics Committee.
Ethics committee address [1] 1083 0
Ethics committee country [1] 1083 0
Australia
Date submitted for ethics approval [1] 1083 0
Approval date [1] 1083 0
Ethics approval number [1] 1083 0
Ethics committee name [2] 1084 0
Balmain Hospital - CSAHS Ethics Review Committee
Ethics committee address [2] 1084 0
Ethics committee country [2] 1084 0
Australia
Date submitted for ethics approval [2] 1084 0
Approval date [2] 1084 0
Ethics approval number [2] 1084 0

Summary
Brief summary
Trial website
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 35563 0
Address 35563 0
Country 35563 0
Phone 35563 0
Fax 35563 0
Email 35563 0
Contact person for public queries
Name 9314 0
Nathan de Vos
Address 9314 0
School of Exercise and Sport Science
Faculty of Health Sciences
University of Sydney
Cumberland Campus
East Street
Lidcombe NSW 2141
Country 9314 0
Australia
Phone 9314 0
N/A
Fax 9314 0
Email 9314 0
[email protected]
Contact person for scientific queries
Name 242 0
Nathan de Vos
Address 242 0
School of Exercise and Sport Science
Faculty of Health Sciences
University of Sydney
Cumberland Campus
East Street
Lidcombe NSW 2141
Country 242 0
Australia
Phone 242 0
N/A
Fax 242 0
Email 242 0
[email protected]

No information has been provided regarding IPD availability


What supporting documents are/will be available?

No Supporting Document Provided



Results publications and other study-related documents

Documents added manually
No documents have been uploaded by study researchers.

Documents added automatically
No additional documents have been identified.